Fc Fragment of IgE Receptor Ia (FCER1A) Peptide
FCER1A
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939615
Quick Overview for Fc Fragment of IgE Receptor Ia (FCER1A) Peptide (ABIN939615)
Target
Fc epsilon RI/FCER1A (FCER1A)
(Fc Fragment of IgE Receptor Ia (FCER1A))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IYYKDGEALK YWYENHNISI TNATVEDSGT YYCTGKVWQL DYESEPLNIT
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of FCER1 A antibody,
Alternative Names: FCER1A control peptide, FCER1A antibody Blocking Peptide, Anti-FCER1A Blocking Peptide, Fc Fragment Of Ige High Affinity I Receptor For, Alpha Polypeptide Blocking Peptide, FCE1A Blocking Peptide, FcERI Blocking Peptide, FCER1A, FCERA-1, FCERA 1, FCERA-1 Blocking Peptide, FCERA 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Background
- The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response.
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Molecular Weight
- 27 kDa
Target
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